Section V - Comparison of Selected Malformation Prevalence with Other Birth Defects Registries
Introduction to Table
The CMR relies on reports from hospitals and physicians for case ascertainment. Underreporting is an obvious concern, and the CMR monitors hospital reporting and follows up if there appears to be underreporting. In this section, CMR live birth prevalence are compared with the prevalences of two other registries, the Metropolitan Atlanta Congenital Defects Program (MACDP)1 and the California Birth Defects Monitoring Program (CBDMP)2. These two registries send data collection specialists to hospitals to identify and abstract records of children with malformations. To help evaluate possible underreporting, CMR prevalences of selected malformations, defined using BPA codes, were compared with prevalence from these two registries. (See Appendix 4 for further information on these BPA codes.) These two programs follow children through one year of age. The CMR follows children through two years; however, more than 95% of cases are reported in the first year. Most of the malformations in this table are recognized at birth. The exceptions are fetal alcohol syndrome and some cardiac malformations.
The most striking difference among the registries is the low prevalence of anencephaly in New York State. This probably is largely due to the inclusion of stillborn infants in the MACDP and the CBDMP. The CMR includes only live born children (see Section VI, Current Topics). Underreporting is not the only reason for possible differences. The prevalences of some birth defects differ by race. True geographic differences may also exist3.
Comparison of Selected Malformation Prevalence
with two other Birth Defects Registries
|D02||Trans of great vessels||4.8||4.7||4.6|
|D03||Tetralogy of Fallot||4.8||2.7||2.9|
|D05||Ventricular septal defect||34.5||21.6||14.8|
|D26||Coarctation of aorta||4.1||4.2||4.0|
|F02||Cleft lip ± cleft palate||7.7||9.9||10.9|
|F16||Rectal/large intestine atresia||4.2||2.7||4.2|
|K01||Reduct deform of upper limb||3.0||4.2||3.1|
|K02||Reduct deform of lower limb||1.9||2.5||1.2|
|S02||Fetal alcohol syndrome||2.0||3.0||0.9|
- Edmonds LD, Layde PM, Levy JM, et al. Congenital malformations surveillance: two American systems. Inter J Epidemiol 1981; 10:247-251.
- Grether JK. New California program monitors birth defects. J Perinatology 1985; 5:8-10.
- Schulman J, Edmonds LD, McClern AB, et al. Surveillance for and comparison of birth defect prevelences in
two geographic areas - United States 1983-1988. In: CDC Surveillance Summaries; March 19, 1993. Morbidity
and Mortality Weekly Report 1993; 42(No. SS-1):1-7.
- Birth defects surveillance data from selected states, A report from the National Birth Defects Prevention Network. Teratology 1997; 56:115-175.