Congenital Malformations Registry - Summary Report

Section I: Demographic Characteristics of Children Reported with Major Malformations

Introduction to Tables

These tables are based on children resident in New York State who were live born in 2002 to 2004 and reported to the registry with major malformations. Since a new coding system was instituted in 1992, the list of major malformations has been revised (see Appendix 3). Thus, the prevalence rates in this report are not comparable to reports prior to 1992.

The overall occurrences of major malformations for the two years ranged from 4.3% to 4.4% of live births. Male children have a higher rate of major malformations than female children (5.2% to 5.4% versus 3.4%, Tables 1a and 1b). This difference is consistent within different racial groups. The rates for major malformations are somewhat higher for black than for white children (5.5% to 5.6% versus 4.1% to 4.2%). The major malformation rate among children with residence at birth in New York State excluding New York City was comparable to that among children with residence at birth in New York City (4.3% to 4.5% versus 4.3%). The smaller number of births in the "other" racial category makes these rates difficult to interpret.

About 79% of children reported with major malformations have only one major malformation (Tables 2a and 2b). Since most children had one major malformation, the race-sex patterns seen for all major malformations are similar to the patterns seen in children with a single major malformation (Tables 3a and 3b). All race-sex groups for children with multiple major malformations showed little variation (Tables 4a and 4b)

Section 1 - Table 1a
2002 Births - New York State Residents
Percent of Live Births with One or More Major Malformations
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 11,008 250,793 4.4 6,882 128,472 5.4 4,126 122,321 3.4
- Non-Hispanic White 5,443 129,899 4.2 3,544 66,642 5.3 1,899 63,257 3.0
- Non-Hispanic Black 2,572 44,956 5.7 1,502 22,838 6.6 1,070 22,118 4.8
- Hispanic 2,206 54,264 4.1 1,340 27,825 4.8 866 26,439 3.3
- Others/Unknown 787 21,674 3.6 496 11,167 4.4 291 10,507 2.8
- All Races 5,742 132,857 4.3 3,683 68,133 5.4 2,059 64,724 3.2
- Non-Hispanic White 4,118 97,855 4.2 2,680 50,179 5.3 1,438 47,676 3.0
- Non-Hispanic Black 801 14,075 5.7 486 7,143 6.8 315 6,932 4.5
- Hispanic 570 14,817 3.8 361 7,690 4.7 209 7,127 2.9
- Others/Unknown 253 6,110 4.1 156 3,121 5.0 97 2,989 3.2
- All Races 5,266 117,936 4.5 3,199 60,339 5.3 2,067 57,597 3.6
- Non-Hispanic White 1,325 32,044 4.1 864 16,463 5.2 461 15,581 3.0
- Non-Hispanic Black 1,771 30,881 5.7 1,016 15,695 6.5 755 15,186 5.0
- Hispanic 1,636 39,447 4.1 979 20,135 4.9 657 19,312 3.4
- Others/Unknown 534 15,564 3.4 340 8,046 4.2 194 7,518 2.6
Section 1 - Table 1b
2003 Births - New York State Residents
Percent of Live Births with One or More Major Malformations
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 11,036 252,997 4.4 6,757 129,715 5.2 4,279 123,282 3.5
- Non-Hispanic White 5,528 131,762 4.2 3,505 67,837 5.2 2,023 63,925 3.2
- Non-Hispanic Black 2,484 43,733 5.7 1,432 22,235 6.4 1,052 21,498 4.9
- Hispanic 2,246 54,695 4.1 1,347 27,779 4.8 899 26,916 3.3
- Others/Unknown 778 22,807 3.4 473 11,864 4.0 305 10,943 2.8
- All Races 5,798 133,529 4.3 3,651 68,358 5.3 2,147 65,171 3.3
- Non-Hispanic White 4,142 98,086 4.2 2,651 50,444 5.3 1,491 47,642 3.1
- Non-Hispanic Black 855 13,862 6.2 500 7,010 7.1 355 6,852 5.2
- Hispanic 589 15,322 3.8 364 7,674 4.7 225 7,648 2.9
- Others/Unknown 212 6,259 3.4 136 3,230 4.2 76 3,029 2.5
- All Races 5,238 119,468 4.4 3,106 61,357 5.1 2,132 58,111 3.7
- Non-Hispanic White 1,386 33,676 4.1 854 17,393 4.9 532 16,283 3.3
- Non-Hispanic Black 1,629 29,871 5.5 932 15,225 6.1 697 14,646 4.8
- Hispanic 1,657 39,373 4.2 983 20,105 4.9 674 19,268 3.5
- Others/Unknown 566 16,548 3.4 337 8,634 3.9 229 7,914 2.9
Section 1 - Table 1c
2004 Births - New York State Residents
Percent of Live Births with One or More Major Malformations
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 11,678 246,169 4.7 7,239 125,982 5.7 4,439 120,187 3.7
- Non-Hispanic White 5,708 124,776 4.6 3,675 63,893 5.8 2,033 60,883 3.3
- Non-Hispanic Black 2,603 41,345 6.3 1,513 21,014 7.2 1,090 20,331 5.4
- Hispanic 2,436 56,426 4.3 1,475 28,763 5.1 961 27,663 3.5
- Others/Unknown 931 23,622 3.9 576 12,312 4.7 355 11,310 3.1
- All Races 6,120 127,612 4.8 3,918 65,380 6.0 2,202 62,232 3.5
- Non-Hispanic White 4,288 91,596 4.7 2,781 46,903 5.9 1,507 44,693 3.4
- Non-Hispanic Black 782 11,929 6.6 487 6,095 8.0 295 5,834 5.1
- Hispanic 775 17,168 4.5 483 8,809 5.5 292 8,359 3.5
- Others/Unknown 275 6,919 4.0 167 3,573 4.7 108 3,346 3.2
- All Races 5,558 118,557 4.7 3,321 60,602 5.5 2,237 57,955 3.9
- Non-Hispanic White 1,420 33,180 4.3 894 16,990 5.3 526 16,190 3.2
- Non-Hispanic Black 1,821 29,416 6.2 1,026 14,919 6.9 795 14,497 5.5
- Hispanic 1,661 39,258 4.2 992 19,954 5.0 669 19,304 3.5
- Others/Unknown 656 16,703 3.9 409 8,739 4.7 247 7,964 3.1
Section 1 - Table 2a
2002 Births - New York State Residents
Number of Major Malformations Per Child
Number of Malformations Number of Children Percent
1 9,006 81.8
2 1,353 12.3
3 404 3.7
4 147 1.3
5 58 0.5
6 23 0.2
7 9 0.1
8 7 0.1
10 1 *
All Children 11,008 100.0
Section 1 - Table 2b
2003 Births - New York State Residents
Number of Major Malformations Per Child
Number of Malformations Number of Children Percent
1 8,966 81.2
2 1,387 12.6
3 421 3.8
4 150 1.4
5 65 0.6
6 23 0.2
7 14 0.1
8 6 0.1
9 3 *
10 1 *
All Children 11,036 100.0
Section 1 - Table 2c
2004 Births - New York State Residents
Number of Major Malformations Per Child
Number of Malformations Number of Children Percent
1 9,539 86.4
2 1,414 12.8
3 428 3.9
4 171 1.5
5 81 0.7
6 27 0.2
7 9 0.1
8 5 0.0
9 2 *
10 1 *
11 1 *
All Children 11,678 100.0

* - Less than 0.05%

Note: Total percent may not add to 100% due to rounding

Section 1 - Table 3a
2002 Births - New York State Residents
Percent of Live Births with One Major Malformation
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 9,006 250,793 3.6 5,718 128,472 4.5 3,288 122,321 2.7
- Non-Hispanic White 4,455 129,899 3.4 2,970 66,642 4.5 1,485 63,257 2.3
- Non-Hispanic Black 2,103 44,956 4.7 1,242 22,838 5.4 861 22,118 3.9
- Hispanic 1,809 54,264 3.3 1,109 27,825 4.0 700 26,439 2.6
- Others/Unknown 639 21,674 2.9 397 11,167 3.6 242 10,507 2.3
- All Races 4,673 132,857 3.5 3,048 68,133 4.5 1,625 64,724 2.5
- Non-Hispanic White 3,367 97,855 3.4 2,238 50,179 4.5 1,129 47,676 2.4
- Non-Hispanic Black 659 14,075 4.7 404 7,143 5.7 255 6,932 3.7
- Hispanic 451 14,817 3.0 288 7,690 3.7 163 7,127 2.3
- Others/Unknown 196 6,110 3.2 118 3,121 3.8 78 2,989 2.6
- All Races 4,333 117,936 3.7 2,670 60,339 4.4 1,663 57,597 2.9
- Non-Hispanic White 1,088 32,044 3.4 732 16,463 4.4 356 15,581 2.3
- Non-Hispanic Black 1,444 30,881 4.7 838 15,695 5.3 606 15,186 4.0
- Hispanic 1,358 39,447 3.4 821 20,135 4.1 537 19,312 2.8
- Others/Unknown 443 15,564 2.8 279 8,046 3.5 164 7,518 2.2
Section 1 - Table 3b
2003 Births - New York State Residents
Percent of Live Births with One Major Malformation
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 8,966 252,997 3.5 5,579 129,715 4.3 3,387 123,282 2.7
- Non-Hispanic White 4,496 131,762 3.4 2,905 67,837 4.3 1,591 63,925 2.5
- Non-Hispanic Black 2,030 43,733 4.6 1,163 22,235 5.2 867 21,498 4.0
- Hispanic 1,816 54,695 3.3 1,122 27,779 4.0 694 26,916 2.6
- Others/Unknown 624 22,807 2.7 389 11,864 3.3 235 10,943 2.1
- All Races 4,722 133,529 3.5 3,028 68,358 4.4 1,694 65,171 2.6
- Non-Hispanic White 3,375 98,086 3.4 2,204 50,444 4.4 1,171 47,642 2.5
- Non-Hispanic Black 713 13,862 5.1 419 7,010 6.0 294 6,852 4.3
- Hispanic 468 15,322 3.1 297 7,674 3.9 171 7,648 2.2
- Others/Unknown 166 6,259 2.7 108 3,230 3.3 58 3,029 1.9
- All Races 4,244 119,468 3.6 2,551 61,357 4.2 1,693 58,111 2.9
- Non-Hispanic White 1,121 33,676 3.3 701 17,393 4.0 420 16,283 2.6
- Non-Hispanic Black 1,317 29,871 4.4 744 15,225 4.9 573 14,646 3.9
- Hispanic 1,348 39,373 3.4 825 20,105 4.1 523 19,268 2.7
- Others/Unknown 458 16,548 2.8 281 8,634 3.3 177 7,914 2.2
Section 1 - Table 3c
2004 Births - New York State Residents
Percent of Live Births with One Major Malformation
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 9,539 246,169 3.9 5,979 125,982 4.7 3,560 120,187 3.0
- Non-Hispanic White 4,677 124,776 3.7 3,053 63,893 4.8 1,624 60,883 2.7
- Non-Hispanic Black 2,126 41,345 5.1 1,240 21,014 5.9 886 20,331 4.4
- Hispanic 1,980 56,426 3.5 1,219 28,763 4.2 761 27,663 2.8
- Others/Unknown 756 23,622 3.2 467 12,312 3.8 289 11,310 2.6
- All Races 4,993 127,612 3.9 3,232 65,380 4.9 1,761 62,232 2.8
- Non-Hispanic White 3,497 91,596 3.8 2,300 46,903 4.9 1,197 44,693 2.7
- Non-Hispanic Black 646 11,929 5.4 399 6,095 6.5 247 5,834 4.2
- Hispanic 624 17,168 3.6 397 8,809 4.5 227 8,359 2.7
- Others/Unknown 226 6,919 3.3 136 3,573 3.8 90 3,346 2.7
- All Races 4,546 118,557 3.8 2,747 60,602 4.5 1,799 57,955 3.1
- Non-Hispanic White 1,180 33,180 3.6 753 16,990 4.4 427 16,190 2.6
- Non-Hispanic Black 1,480 29,416 5.0 841 14,919 5.6 639 14,497 4.4
- Hispanic 1,356 39,258 3.5 822 19,954 4.1 534 19,304 2.8
- Others/Unknown 530 16,703 3.2 331 8,739 3.8 199 7,964 2.5
Section 1 - Table 4a
2002 Births - New York State Residents
Percent of Live Births with Two or More Major Malformations
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 2,002 250,793 0.8 1,164 128,472 0.9 838 122,321 0.7
- Non-Hispanic White 988 129,899 0.8 574 66,642 0.9 414 63,257 0.7
- Non-Hispanic Black 469 44,956 1.0 260 22,838 1.1 209 22,118 0.9
- Hispanic 397 54,264 0.7 231 27,825 0.8 166 26,439 0.6
- Others/Unknown 148 21,674 0.7 99 11,167 0.9 49 10,507 0.5
- All Races 1,069 132,857 0.8 635 68,133 0.9 434 64,724 0.7
- Non-Hispanic White 751 97,855 0.8 442 50,179 0.9 309 47,676 0.6
- Non-Hispanic Black 142 14,075 1.0 82 7,143 1.1 60 6,932 0.9
- Hispanic 119 14,817 0.8 73 7,690 0.9 46 7,127 0.6
- Others/Unknown 57 6,110 0.9 38 3,121 1.2 19 2,989 0.6
- All Races 933 117,936 0.8 529 60,339 0.9 404 57,597 0.7
- Non-Hispanic White 237 32,044 0.7 132 16,463 0.8 105 15,581 0.7
- Non-Hispanic Black 327 30,881 1.1 178 15,695 1.1 149 15,186 1.0
- Hispanic 278 39,447 0.7 158 20,135 0.8 120 19,312 0.6
- Others/Unknown 91 15,564 0.6 61 8,046 0.8 30 7,518 0.4
Section 1 - Table 4b
2003 Births - New York State Residents
Percent of Live Births with Two or More Major Malformations
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 2,070 252,997 0.8 1,178 129,715 0.9 892 123,282 0.7
- Non-Hispanic White 1,032 131,762 0.8 600 67,837 0.9 432 63,925 0.7
- Non-Hispanic Black 454 43,733 1.0 269 22,235 1.2 185 21,498 0.9
- Hispanic 430 54,695 0.8 225 27,779 0.8 205 26,916 0.8
- Others/Unknown 154 22,807 0.7 84 11,864 0.7 70 10,943 0.6
- All Races 1,076 133,529 0.8 623 68,358 0.9 453 65,171 0.7
- Non-Hispanic White 767 98,086 0.8 447 50,444 0.9 320 47,642 0.7
- Non-Hispanic Black 142 13,862 1.0 81 7,010 1.2 61 6,852 0.9
- Hispanic 121 15,322 0.8 67 7,674 0.9 54 7,648 0.7
- Others/Unknown 46 6,259 0.7 28 3,230 0.9 18 3,029 0.6
- All Races 994 119,468 0.8 555 61,357 0.9 439 58,111 0.8
- Non-Hispanic White 265 33,676 0.8 153 17,393 0.9 112 16,283 0.7
- Non-Hispanic Black 312 29,871 1.0 188 15,225 1.2 124 14,646 0.8
- Hispanic 309 39,373 0.8 158 20,105 0.8 151 19,268 0.8
- Others/Unknown 108 16,548 0.7 56 8,634 0.6 52 7,914 0.7
Section 1 - Table 4c
2004 Births - New York State Residents
Percent of Live Births with Two or More Major Malformations
Sex by Race/Ethnicity and Residence
  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
- All Races 2,139 246,169 0.9 1,260 125,982 1.0 879 120,187 0.7
- Non-Hispanic White 1,031 124,776 0.8 622 63,893 1.0 409 60,883 0.7
- Non-Hispanic Black 477 41,345 1.2 273 21,014 1.3 204 20,331 1.0
- Hispanic 456 56,426 0.8 256 28,763 0.9 200 27,663 0.7
- Others/Unknown 175 23,622 0.7 109 12,312 0.9 66 11,310 0.6
- All Races 1,127 127,612 0.9 686 65,380 1.0 441 62,232 0.7
- Non-Hispanic White 791 91,596 0.9 481 46,903 1.0 310 44,693 0.7
- Non-Hispanic Black 136 11,929 1.1 88 6,095 1.4 48 5,834 0.8
- Hispanic 151 17,168 0.9 86 8,809 1.0 65 8,359 0.8
- Others/Unknown 49 6,919 0.7 31 3,573 0.9 18 3,346 0.5
- All Races 1,012 118,557 0.9 574 60,602 0.9 438 57,955 0.8
- Non-Hispanic White 240 33,180 0.7 141 16,990 0.8 99 16,190 0.6
- Non-Hispanic Black 341 29,416 1.2 185 14,919 1.2 156 14,497 1.1
- Hispanic 305 39,258 0.8 170 19,954 0.9 135 19,304 0.7
- Others/Unknown 126 16,703 0.8 78 8,739 0.9 48 7,964 0.6