Congenital Malformations Registry - Summary Report

Section III: Prevalence of Selected Malformations by Sex and Race/Ethnicity

Introduction to Tables

The malformations presented in this section were selected because of the frequency with which they were reported and/or their clinical significance. Rates are per 10,000 live births. The sex ratio is calculated by dividing the rate in males by the rate in females. The malformation rates presented in this report may not be comparable to earlier reports. Previous reports from 1989 to 1991 did not use birth certificate matched cases; thus, the race and birth weight from the birth certificate were not available. Birth weight data are useful to calculate the rate of some malformations such as Patent Ductus Arteriosus. In some cases, these conditions can result from being preterm rather than actually having a malformation. Racial data in this report also may not be comparable because race is defined by maternal race from the birth certificate. In the earlier reports, race was defined by what was reported on the CMR form, which may differ from what is recorded on the birth certificate.

Fluctuations in specific malformation prevalence should be interpreted with caution, especially differences in the "other" race category since the numbers in this group are small. In addition, several malformations were added in 1992 as a result of the change to the BPA coding system. Previously, these could not be distinguished using the ICD-9 codes. However, since ICD-9 codes are more familiar to most vendors, the ICD-9 code is given on the table with the named malformation. See Appendix 3 for further information on the BPA codes.

Section III - Table 1: Children with Selected Malformations Prevalence per 10,000 Live Births by Sex and Race/Ethnicity

2002 Births– New York State Residents
ICD-9 Malformation Total Number Total Prevalence Male Female Ratio (M/F) Non-Hispanic White Non-Hispanic Black Hispanic Other/ Unknown Race
243 Congenital hypothyroidism 55 2.2 2.1 2.3 0.9 1.5 4.7 1.7 2.3
270.1 Phenylketonuria 3 0.1 0.2 0.0 0.0 0.2 0.0 0.2 0.0
277.0 Cystic fibrosis 26 1.0 0.9 1.1 0.8 1.5 0.4 0.7 0.0
282.6 Sickle-cell anemia 79 3.2 3.0 3.4 0.9 0.2 14.9 1.7 0.0
740.0 Anencephalus 8 0.3 0.3 0.3 1.0 0.2 0.9 0.2 0.0
741.0 Spina bifida with hydrocephalus 31 1.2 1.2 1.2 1.0 1.1 1.1 1.8 0.9
741.9 Spina bifida without hydrocephalus 19 0.8 0.7 0.8 0.9 0.8 0.4 1.1 0.5
742.0 Encephalocele 14 0.6 0.6 0.5 1.3 0.5 0.4 0.9 0.0
742.1 Microcephalus 124 4.9 4.4 5.6 0.8 1.9 10.7 8.3 2.8
742.2 Agyria & lissencephaly 4 0.2 0.2 0.1 2.9 0.2 0.4 0.0 0.0
742.2 Anomalies of corpus callosum 39 1.6 1.9 1.1 1.7 1.5 1.8 1.7 1.4
742.2 Holoprosencephaly 17 0.7 0.5 0.8 0.7 0.7 0.7 0.7 0.5
742.3 Congenital hydrocephalus 178 7.1 8.5 5.6 1.5 5.2 11.1 8.8 5.5
742.4 Porencephaly 10 0.4 0.5 0.2 2.2 0.5 0.4 0.2 0.0
742.5 Congenital tethered cord 15 0.6 0.5 0.7 0.6 0.6 0.2 0.9 0.5
743.0 Anophthalmos 1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0
743.1 Microphthalmos 18 0.7 1.0 0.4 2.5 0.6 1.1 0.9 0.0
743.2 Glaucoma 14 0.6 0.7 0.4 1.7 0.5 0.2 1.3 0.0
743.3 Absence of lens 8 0.3 0.4 0.2 1.6 0.2 0.7 0.2 0.5
743.3 Congenital cataract 22 0.9 0.9 0.9 1.0 0.6 1.3 1.1 0.9
743.45 Aniridia 1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0
743.46 Coloboma of iris 2 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0
744.0 Anotia/microtia 15 0.6 0.5 0.7 0.8 0.6 0.2 0.6 1.4
745.0 Common truncus 15 0.6 0.2 1.0 0.2 0.4 0.9 0.9 0.5
745.1 Transposition of great vessels 124 4.9 5.8 4.1 1.4 4.8 4.4 5.7 5.1
745.2 Tetralogy of Fallot 104 4.1 4.1 4.2 1.0 4.0 4.2 3.1 7.4
745.3 Common ventricle 11 0.4 0.5 0.3 1.7 0.4 0.0 1.1 0.0
745.4 Ventricular septal defect 843 33.6 32.3 35.0 0.9 35.3 35.4 30.0 28.6
745.5 Ostium secundum type atrial septal def. 1,347 53.7 54.9 52.5 1.0 48.5 91.9 39.1 42.4
745.6 Endocardial cushion defects 84 3.3 3.0 3.8 0.8 2.8 5.1 3.3 2.8
746.0 Atresia/stenosis of pulmonary valve 210 8.4 8.3 8.5 1.0 7.9 11.1 8.1 6.0
746.1 Tricuspid Atresia/stenosis/hypoplasia 32 1.3 1.7 0.8 2.1 1.2 2.4 0.7 0.5
746.2 Ebstein's anomaly 18 0.7 0.7 0.7 1.0 0.6 0.7 0.7 1.4
746.3 Congenital stenosis of aortic valve 26 1.0 1.2 0.8 1.5 1.2 0.9 0.7 0.9
746.7 Hypoplastic left heart syndrome 55 2.2 2.5 1.9 1.3 1.5 2.9 3.7 1.4
746.85 Anomalies of coronary artery 9 0.4 0.4 0.3 1.2 0.2 0.4 0.6 0.9
747.0 Patent ductus arteriosis 488 19.5 19.9 19.0 1.1 14.8 35.6 16.2 22.1
747.10 Coarctation of aorta 119 4.7 5.1 4.3 1.2 5.2 5.8 3.9 2.3
747.41 Total anomalous pulmonary venus connect. 30 1.2 1.3 1.1 1.2 1.0 1.1 1.8 0.9
748.0 Choanal Atresia 44 1.8 1.5 2.0 0.7 1.8 2.0 1.1 2.3
748.5 Agenesis/hypoplasia of lung 54 2.2 2.6 1.6 1.6 2.5 1.8 2.4 0.0
749.0 Cleft palate 148 5.9 5.4 6.5 0.8 6.8 4.0 5.0 6.9
749.1 Cleft lip 52 2.1 2.3 1.8 1.3 2.5 0.9 2.4 1.4
749.2 Cleft palate & lip 131 5.2 7.0 3.4 2.1 4.9 4.9 5.3 7.4
750.3 Tracheoesophageal fistula etc. 56 2.2 2.4 2.0 1.2 2.6 2.0 2.0 0.9
750.5 Congenital hypertrophic pyloric stenosis 372 14.8 23.8 5.4 4.4 16.7 7.1 18.4 10.6
751.1 Atresia and stenosis of small intestine 100 4.0 3.7 4.3 0.9 3.6 5.1 4.4 2.8
751.2 Atresia and stenosis of rectum or anus 105 4.2 4.2 4.2 1.0 4.8 2.7 4.4 3.2
751.3 Hirschsprungs disease 72 2.9 4.3 1.4 3.1 2.9 3.3 2.8 1.8
751.4 Anomalies of intestinal fixation 42 1.7 1.9 1.4 1.4 1.9 2.7 0.7 0.5
751.61 Biliary Atresia 26 1.0 1.1 1.0 1.1 0.8 0.9 0.9 2.8
752.6 Epispadias 22 0.9 1.6 0.1 20.0 1.0 0.9 0.7 0.5
752.6 Hypospadias 881 35.1 68.1 0.5 138.9 44.4 32.3 20.1 23.1
753.0 Renal agenesis and dysgenesis 81 3.2 3.7 2.8 1.3 3.2 3.3 3.3 2.8
753.1 Cystic kidney disease 147 5.9 6.2 5.5 1.1 5.2 7.3 6.4 5.1
753.2 Obstructive defect renal pelvis & ureter 801 31.9 44.2 19.0 2.3 33.4 26.2 34.5 28.6
753.5 Extrophy of urinary bladder 5 0.2 0.2 0.2 1.4 0.2 0.0 0.0 0.9
753.6 Atresia & stenosis of urethra & bladder 12 0.5 0.9 0.0 0.0 0.8 0.2 0.2 0.0
754.3 Congenital dislocation of hip 251 10.0 4.0 16.3 0.2 11.9 4.2 11.2 7.4
754.51 Talipes equinovarus 298 11.9 14.5 9.2 1.6 10.8 13.6 12.7 12.9
755.2 Reduction deformities of upper limb 44 1.8 1.5 2.0 0.7 2.0 1.6 1.7 0.9
755.3 Reduction deformities of lower limb 27 1.1 1.5 0.7 2.3 1.2 1.1 0.7 0.9
755.8 Arthrogryposis multiplex congenita 14 0.6 0.5 0.6 1.0 0.6 0.9 0.4 0.0
756.0 Craniosynostosis 92 3.7 4.3 3.0 1.4 4.5 3.1 2.6 2.8
756.0 Goldenhar syndrome 9 0.4 0.3 0.4 0.8 0.5 0.2 0.2 0.5
756.4 Chonodrodystrophy 22 0.9 0.9 0.8 1.1 0.5 2.0 1.1 0.0
756.51 Osteogenesis imperfecta 6 0.2 0.3 0.2 1.9 0.3 0.4 0.0 0.0
756.6 Diaphragmatic hernia 41 1.6 1.2 2.0 0.6 1.8 1.3 1.5 1.8
756.7 Gastroschisis 50 2.0 2.0 2.0 1.0 2.1 1.6 2.6 0.9
756.7 Omphalocele 35 1.4 1.7 1.1 1.6 1.5 1.1 1.7 0.9
756.7 Prune belly 5 0.2 0.4 0.0 0.0 0.0 0.7 0.4 0.0
758.0 Down syndrome 290 11.6 12.2 10.9 1.1 11.8 14.2 10.1 8.3
758.1 Patau syndrome 19 0.8 0.9 0.6 1.6 0.6 1.1 0.9 0.5
758.2 Edwards syndrome 29 1.2 0.7 1.6 0.4 1.5 1.6 0.6 0.0
758.6 Gonadal dysgenesis 12 0.5 0.2 0.8 0.2 0.5 0.2 0.6 0.5
758.7 Klinefelter syndrome 17 0.7 1.3 0.0 0.0 0.6 0.2 1.3 0.5
759.3 Situs inversus 15 0.6 0.9 0.3 2.6 0.5 0.9 0.6 0.5
760.71 Fetal alcohol syndrome 20 0.8 0.8 0.8 1.0 0.6 1.8 0.6 0.5
771.0 Congenital rubella 1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0
771.1 Congenital cytomegalovirus infection 16 0.6 0.5 0.8 0.6 0.5 1.6 0.4 0.5
771.2 Other congenital infections 32 1.3 1.9 0.7 2.9 0.8 1.8 1.8 1.4

Section III - Table 2: Children with Selected Malformations Prevalence per 10,000 Live Births by Sex and Race/Ethnicity

2003 Births– New York State Residents
ICD-9 Malformation Total Number Total Prevalence Male Female Ratio (M/F) Non-Hispanic White Non-Hispanic Black Hispanic Other/ Unknown Race
243 Congenital hypothyroidism 87 3.4 4.2 2.7 1.6 2.5 5.9 2.9 5.3
270.1 Phenylketonuria 3 0.1 0.2 0.1 1.9 0.2 0.0 0.2 0.0
277.0 Cystic fibrosis 16 0.6 0.8 0.4 2.1 1.0 0.2 0.2 0.4
282.6 Sickle-cell anemia 84 3.3 3.3 3.3 1.0 0.1 16.7 1.6 0.4
740.0 Anencephalus 11 0.4 0.5 0.4 1.1 0.5 0.5 0.2 0.4
741.0 Spina bifida with hydrocephalus 29 1.1 0.5 1.8 0.3 1.1 1.1 1.3 1.3
741.9 Spina bifida without hydrocephalus 21 0.8 0.5 1.2 0.4 0.6 0.7 1.6 0.4
742.0 Encephalocele 16 0.6 0.6 0.6 1.0 0.8 0.9 0.4 0.0
742.1 Microcephalus 118 4.7 4.3 5.0 0.9 3.6 7.5 5.7 2.6
742.2 Agyria & lissencephaly 7 0.3 0.3 0.2 1.3 0.3 0.0 0.4 0.4
742.2 Anomalies of corpus callosum 41 1.6 1.7 1.5 1.1 1.4 3.0 0.7 2.2
742.2 Holoprosencephaly 10 0.4 0.2 0.6 0.4 0.2 0.2 1.1 0.0
742.3 Congenital hydrocephalus 189 7.5 8.0 6.9 1.2 5.8 12.1 7.9 7.5
742.4 Porencephaly 11 0.4 0.5 0.4 1.1 0.3 0.7 0.7 0.0
742.5 Congenital tethered cord 24 0.9 0.9 1.0 1.0 1.3 0.0 0.9 0.9
743.0 Anophthalmos 2 0.1 0.1 0.1 1.0 0.1 0.0 0.2 0.0
743.1 Microphthalmos 9 0.4 0.3 0.4 0.8 0.3 0.0 0.9 0.0
743.2 Glaucoma 6 0.2 0.4 0.1 4.8 0.4 0.2 0.0 0.0
743.3 Absence of lens 11 0.4 0.4 0.5 0.8 0.5 0.2 0.4 0.9
743.3 Congenital cataract 22 0.9 0.7 1.1 0.7 1.1 0.7 0.5 0.9
743.46 Coloboma of iris 5 0.2 0.3 0.1 3.8 0.3 0.2 0.0 0.0
744.0 Anotia/microtia 15 0.6 0.5 0.6 0.8 0.5 0.5 1.1 0.0
745.0 Common truncus 16 0.6 0.6 0.6 1.0 0.4 1.4 0.7 0.4
745.1 Transposition of great vessels 111 4.4 5.1 3.7 1.4 4.8 3.7 4.0 4.4
745.2 Tetralogy of Fallot 123 4.9 5.6 4.1 1.3 4.8 4.6 5.1 5.3
745.3 Common ventricle 17 0.7 0.6 0.7 0.8 0.5 1.1 0.7 0.9
745.4 Ventricular septal defect 917 36.2 32.2 40.5 0.8 36.9 34.3 36.6 35.5
745.5 Ostium secundum type atrial septal def. 1,036 40.9 40.2 41.7 1.0 33.9 59.2 43.1 41.2
745.6 Endocardial cushion defects 66 2.6 2.8 2.4 1.1 3.0 2.5 2.2 1.3
746.0 Atresia/stenosis of pulmonary valve 254 10.0 9.9 10.1 1.0 8.8 13.7 9.3 11.8
746.1 Tricuspid Atresia/stenosis/hypoplasia 28 1.1 1.2 1.1 1.1 0.7 2.5 0.9 1.3
746.2 Ebstein's anomaly 13 0.5 0.5 0.6 0.8 0.5 0.0 0.5 1.8
746.3 Congenital stenosis of aortic valve 34 1.3 1.9 0.7 2.6 1.8 0.9 0.7 0.9
746.7 Hypoplastic left heart syndrome 70 2.8 3.0 2.5 1.2 3.0 3.0 2.6 1.8
746.85 Anomalies of coronary artery 10 0.4 0.3 0.5 0.6 0.5 0.5 0.2 0.4
747.0 Patent ductus arteriosis 722 28.5 27.3 29.9 0.9 26.2 48.0 19.9 25.4
747.10 Coarctation of aorta 121 4.8 4.9 4.6 1.1 5.2 5.5 3.8 3.5
747.41 Total anomalous pulmonary venus connect. 18 0.7 0.6 0.8 0.8 0.5 0.7 1.5 0.0
748.0 Choanal Atresia 35 1.4 1.5 1.2 1.3 1.7 0.9 1.3 0.4
748.5 Agenesis/hypoplasia of lung 74 2.9 3.0 2.8 1.1 2.9 4.1 2.9 0.9
749.0 Cleft palate 133 5.3 5.2 5.3 1.0 5.2 4.3 5.5 7.0
749.1 Cleft lip 63 2.5 2.8 2.2 1.3 3.7 1.1 1.5 0.4
749.2 Cleft palate & lip 120 4.7 5.6 3.9 1.4 4.7 4.1 5.7 3.9
750.3 Tracheoesophageal fistula etc. 60 2.4 2.6 2.1 1.2 3.1 1.8 1.5 1.3
750.5 Congenital hypertrophic pyloric stenosis 362 14.3 22.6 5.6 4.0 15.7 8.2 18.8 7.0
751.1 Atresia and stenosis of small intestine 103 4.1 4.5 3.6 1.3 3.7 5.7 3.8 3.5
751.2 Atresia and stenosis of rectum or anus 117 4.6 4.5 4.8 0.9 4.3 4.1 5.9 4.8
751.3 Hirschsprungs disease 52 2.1 3.1 1.0 3.2 2.4 2.3 1.3 1.8
751.4 Anomalies of intestinal fixation 32 1.3 1.6 0.9 1.8 1.7 0.7 0.5 1.3
751.61 Biliary Atresia 24 0.9 1.2 0.7 1.6 0.8 0.7 1.1 1.8
752.6 Epispadias 23 0.9 1.8 0.0 0.0 1.2 0.9 0.4 0.4
752.6 Hypospadias 871 34.4 67.0 0.2 413.0 40.5 35.0 24.5 22.4
753.0 Renal agenesis and dysgenesis 81 3.2 4.1 2.3 1.8 4.2 2.7 2.2 0.9
753.1 Cystic kidney disease 134 5.3 5.5 5.1 1.1 5.2 5.5 6.2 3.1
753.2 Obstructive defect renal pelvis & ureter 789 31.2 41.6 20.3 2.0 33.9 23.8 29.8 32.9
753.5 Extrophy of urinary bladder 5 0.2 0.2 0.2 0.6 0.2 0.2 0.2 0.0
753.6 Atresia & stenosis of urethra & bladder 18 0.7 1.3 0.1 16.2 0.6 1.4 0.7 0.0
754.3 Congenital dislocation of hip 254 10.0 5.6 14.7 0.4 11.1 5.9 10.4 11.0
754.51 Talipes equinovarus 207 8.2 9.9 6.4 1.5 8.4 6.6 9.9 5.7
755.2 Reduction deformities of upper limb 54 2.1 2.4 1.9 1.3 2.7 1.6 1.5 1.3
755.3 Reduction deformities of lower limb 25 1.0 1.3 0.6 2.0 1.1 1.1 0.9 0.4
755.8 Arthrogryposis multiplex congenita 11 0.4 0.2 0.6 0.4 0.5 0.2 0.7 0.0
756.0 Craniosynostosis 98 3.9 4.2 3.6 1.2 4.6 2.7 3.5 2.6
756.0 Goldenhar syndrome 5 0.2 0.3 0.1 3.8 0.2 0.2 0.4 0.0
756.4 Chonodrodystrophy 30 1.2 1.0 1.4 0.7 1.0 2.3 0.9 0.9
756.51 Osteogenesis imperfecta 9 0.4 0.2 0.5 0.5 0.4 0.5 0.4 0.0
756.6 Diaphragmatic hernia 59 2.3 2.8 1.9 1.5 2.7 2.1 2.6 0.4
756.7 Gastroschisis 44 1.7 1.9 1.6 1.1 1.5 2.3 2.0 1.3
756.7 Omphalocele 30 1.2 1.3 1.1 1.2 0.8 1.8 1.5 1.3
756.7 Prune belly 1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0
758.0 Down syndrome 319 12.6 12.9 12.3 1.0 13.1 12.3 11.5 12.7
758.1 Patau syndrome 20 0.8 1.0 0.6 1.8 0.6 1.6 0.5 0.9
758.2 Edwards syndrome 32 1.3 1.2 1.3 1.0 0.8 2.5 1.3 1.8
758.6 Gonadal dysgenesis 15 0.6 0.1 1.1 0.1 0.5 0.9 0.5 0.4
758.7 Klinefelter syndrome 9 0.4 0.7 0.0 0.0 0.3 0.2 0.7 0.0
759.3 Situs inversus 26 1.0 1.0 1.1 1.0 0.8 1.6 1.1 0.9
760.71 Fetal alcohol syndrome 6 0.2 0.3 0.2 1.9 0.1 0.7 0.4 0.0
771.1 Congenital cytomegalovirus infection 12 0.5 0.6 0.3 1.9 0.5 0.5 0.5 0.4
771.2 Other congenital infections 18 0.7 0.8 0.6 1.5 0.7 0.9 0.9 0.0

Section III - Table 3: Children with Selected Malformations Prevalence per 10,000 Live Births by Sex and Race/Ethnicity

2004 Births– New York State Residents
ICD-9 Malformation Total Number Total Prevalence Male Female Ratio (M/F) Non-Hispanic White Non-Hispanic Black Hispanic Other/ Unknown Race
243 Congenital hypothyroidism 101 4.1 4.3 3.9 1.1 3.3 7.0 3.4 5.1
270.1 Phenylketonuria 4 0.2 0.2 0.2 1.0 0.1 0.2 0.2 0.4
277.0 Cystic fibrosis 21 0.9 0.9 0.8 1.0 1.4 0.2 0.5 0.0
282.6 Sickle-cell anemia 134 5.4 5.2 5.7 0.9 0.4 27.8 2.1 0.8
740.0 Anencephalus 13 0.5 0.3 0.7 0.4 0.7 0.2 0.2 0.8
741.0 Spina bifida with hydrocephalus 26 1.1 0.9 1.2 0.7 0.8 1.2 1.4 1.3
741.9 Spina bifida without hydrocephalus 20 0.8 0.7 0.9 0.8 1.0 0.2 0.9 0.4
742.0 Encephalocele 10 0.4 0.5 0.3 1.4 0.4 0.2 0.7 0.0
742.1 Microcephalus 130 5.3 5.4 5.2 1.0 3.9 8.5 6.6 3.8
742.2 Agyria & lissencephaly 6 0.2 0.3 0.2 1.9 0.2 0.7 0.2 0.0
742.2 Anomalies of corpus callosum 50 2.0 2.4 1.7 1.4 1.8 2.7 2.1 2.1
742.2 Holoprosencephaly 11 0.4 0.6 0.3 1.7 0.3 0.7 0.7 0.0
742.3 Congenital hydrocephalus 211 8.6 9.3 7.8 1.2 6.5 14.0 10.1 6.4
742.4 Porencephaly 8 0.3 0.2 0.5 0.3 0.5 0.5 0.0 0.0
742.5 Congenital tethered cord 41 1.7 1.7 1.7 1.0 2.1 1.5 0.9 1.7
743.0 Anophthalmos 2 0.1 0.1 0.1 1.0 0.2 0.0 0.0 0.0
743.1 Microphthalmos 14 0.6 0.6 0.6 1.0 0.4 0.7 0.5 1.3
743.2 Glaucoma 18 0.7 0.8 0.7 1.2 0.6 1.5 0.4 1.3
743.3 Absence of lens 8 0.3 0.4 0.2 1.6 0.2 0.7 0.0 0.8
743.3 Congenital cataract 10 0.4 0.6 0.2 2.2 0.4 0.7 0.2 0.4
743.45 Aniridia 2 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0
743.46 Coloboma of iris 2 0.1 0.1 0.1 1.0 0.2 0.0 0.0 0.0
744.0 Anotia/microtia 20 0.8 0.9 0.7 1.2 1.0 0.2 0.7 0.8
745.0 Common truncus 15 0.6 0.6 0.6 1.1 0.4 1.5 0.4 0.8
745.1 Transposition of great vessels 100 4.1 4.7 3.4 1.4 4.4 4.8 3.9 1.3
745.2 Tetralogy of Fallot 125 5.1 6.6 3.5 1.9 5.5 5.8 3.9 4.2
745.3 Common ventricle 26 1.1 1.0 1.2 0.8 1.0 1.2 1.4 0.4
745.4 Ventricular septal defect 1,039 42.2 39.8 44.8 0.9 42.2 43.1 42.9 39.4
745.5 Ostium secundum type atrial septal def. 1,124 45.7 45.9 45.4 1.0 32.6 86.1 41.8 52.9
745.6 Endocardial cushion defects 69 2.8 2.5 3.1 0.8 2.9 3.4 2.1 3.0
746.0 Atresia/stenosis of pulmonary valve 235 9.5 9.9 9.2 1.1 8.6 15.5 8.3 7.2
746.1 Tricuspid Atresia/stenosis/hypoplasia 21 0.9 0.7 1.0 0.7 0.7 1.7 0.7 0.4
746.2 Ebstein's anomaly 18 0.7 0.8 0.7 1.2 0.7 0.5 0.9 0.8
746.3 Congenital stenosis of aortic valve 31 1.3 1.9 0.6 3.3 1.5 1.0 1.1 0.8
746.7 Hypoplastic left heart syndrome 53 2.2 2.5 1.8 1.3 2.3 3.6 1.4 0.4
746.85 Anomalies of coronary artery 16 0.6 1.0 0.3 2.9 0.9 0.7 0.2 0.4
747.0 Patent ductus arteriosis 803 32.6 30.4 34.9 0.9 29.4 58.3 23.4 26.7
747.10 Coarctation of aorta 118 4.8 6.3 3.2 1.9 5.1 4.6 5.3 2.1
747.41 Total anomalous pulmonary venus connect. 26 1.1 1.2 0.9 1.3 0.6 1.2 2.1 0.4
748.0 Choanal Atresia 40 1.6 1.7 1.5 1.2 2.1 1.5 0.9 1.3
748.5 Agenesis/hypoplasia of lung 58 2.4 2.9 1.8 1.6 2.7 3.6 1.2 0.8
749.0 Cleft palate 133 5.4 4.8 6.0 0.8 5.5 4.4 5.1 7.2
749.1 Cleft lip 50 2.0 2.4 1.7 1.4 2.6 1.7 1.4 1.3
749.2 Cleft palate & lip 105 4.3 5.1 3.4 1.5 4.7 1.5 5.7 3.4
750.3 Tracheoesophageal fistula etc. 60 2.4 2.9 1.9 1.5 2.8 2.7 1.6 2.1
750.5 Congenital hypertrophic pyloric stenosis 549 22.3 35.2 8.7 4.0 25.6 12.3 26.9 11.0
751.1 Atresia and stenosis of small intestine 114 4.6 4.3 5.0 0.9 4.4 4.1 5.5 4.7
751.2 Atresia and stenosis of rectum or anus 111 4.5 5.5 3.5 1.6 4.5 4.8 3.9 5.5
751.3 Hirschsprungs disease 65 2.6 3.9 1.3 2.9 2.6 2.7 2.7 2.5
751.4 Anomalies of intestinal fixation 38 1.5 1.7 1.3 1.3 1.8 2.4 0.2 2.1
751.61 Biliary Atresia 22 0.9 1.1 0.7 1.7 0.6 1.2 1.1 1.3
752.6 Epispadias 25 1.0 1.9 0.1 22.9 1.1 1.9 0.4 0.4
752.6 Hypospadias 873 35.5 69.1 0.2 276.7 44.6 33.1 22.2 22.9
753.0 Renal agenesis and dysgenesis 87 3.5 4.5 2.5 1.8 3.7 4.4 2.5 3.8
753.1 Cystic kidney disease 141 5.7 6.4 5.0 1.3 5.0 7.5 6.6 4.7
753.2 Obstructive defect renal pelvis & ureter 849 34.5 48.6 19.7 2.5 36.9 28.1 35.4 30.9
753.5 Extrophy of urinary bladder 3 0.1 0.2 0.1 1.9 0.1 0.0 0.4 0.0
753.6 Atresia & stenosis of urethra & bladder 13 0.5 1.0 0.0 0.0 0.6 1.0 0.2 0.0
754.3 Congenital dislocation of hip 228 9.3 5.9 12.8 0.5 10.3 5.3 10.1 8.5
754.51 Talipes equinovarus 192 7.8 8.6 7.0 1.2 8.7 10.6 5.5 3.4
755.2 Reduction deformities of upper limb 44 1.8 1.7 1.8 1.0 1.8 1.9 2.1 0.4
755.3 Reduction deformities of lower limb 24 1.0 1.2 0.7 1.6 1.0 1.5 0.9 0.0
755.8 Arthrogryposis multiplex congenita 10 0.4 0.2 0.7 0.2 0.1 1.0 0.7 0.4
756.0 Craniosynostosis 95 3.9 5.1 2.6 2.0 5.3 1.5 3.4 1.7
756.0 Goldenhar syndrome 5 0.2 0.2 0.2 1.4 0.3 0.0 0.2 0.0
756.4 Chonodrodystrophy 34 1.4 1.7 1.0 1.7 1.1 2.2 1.8 0.4
756.51 Osteogenesis imperfecta 10 0.4 0.6 0.2 2.2 0.2 0.7 0.7 0.0
756.6 Diaphragmatic hernia 63 2.6 3.3 1.8 1.8 3.0 2.2 1.9 2.5
756.7 Gastroschisis 49 2.0 2.2 1.7 1.3 2.1 1.2 2.7 1.3
756.7 Omphalocele 33 1.3 1.7 0.9 1.9 1.3 2.2 1.1 0.8
756.7 Prune belly 8 0.3 0.6 0.1 6.7 0.1 1.2 0.2 0.4
758.0 Down syndrome 309 12.6 13.4 11.6 1.2 12.6 13.3 13.5 8.9
758.1 Patau syndrome 22 0.9 1.0 0.7 1.4 0.8 1.2 0.7 1.3
758.2 Edwards syndrome 27 1.1 0.9 1.3 0.7 0.9 2.7 0.5 0.8
758.6 Gonadal dysgenesis 18 0.7 0.1 1.4 0.1 0.9 0.5 0.7 0.4
758.7 Klinefelter syndrome 17 0.7 1.3 0.1 15.3 0.7 0.2 1.1 0.4
759.3 Situs inversus 13 0.5 0.5 0.6 0.8 0.6 0.2 0.5 0.8
760.71 Fetal alcohol syndrome 13 0.5 0.6 0.5 1.1 0.2 2.4 0.0 0.0
771.1 Congenital cytomegalovirus infection 13 0.5 0.6 0.4 1.5 0.2 1.9 0.4 0.4
771.2 Other congenital infections 42 1.7 1.0 2.4 0.4 1.4 2.4 1.8 1.7