Congenital Malformations Registry - Summary Report

Section I: Demographic Characteristics of Children Reported with Major Malformations

Introduction to Tables

These tables are based on children resident in New York State who were live born in 2005 and reported to the registry with major malformations. Since a new coding system began to be used in 1992, the list of major malformations has been revised (see Appendix 4). Thus, the prevalence in this report are not comparable to reports prior to 1992.

The overall occurrence of major malformations was 4.8% of live births. Male children have a higher rate of major malformations than female children (5.8% versus 3.8%, Table 1). This difference is consistent within different racial groups. The rates for major malformations are somewhat higher for black than for white children (6.0 % versus 4.7%). The major malformation rate among children with residence at birth in New York State excluding New York City was comparable to that among children with residence at birth in New York City (4.8% versus 4.8%). The smaller number of births in the "other" racial category makes these rates difficult to interpret.

About 82% of children reported with major malformations have only one major malformation (Table 2). Since most children had one major malformation, the race-sex patterns seen for all major malformations are similar to the patterns seen in children with a single major malformation (Table 3). All race-sex groups for children with multiple major malformations showed little variation (Table 4).

Section 1 - Table 1
2005 Births - New York State Residents Percent of Live Births with One or More Major Malformations Sex by Race/Ethnicity and Residence

  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
New York State
- All Races 11,676 242,659 4.8 7,228 124,392 5.8 4,448 118,267 3.8
- Non-Hispanic White 5,699 121,416 4.7 3,623 62,184 5.8 2,076 59,232 3.5
- Non-Hispanic Black 2,442 40,772 6.0 1,430 20,857 6.9 1,012 19,915 5.1
- Hispanic 2,589 56,558 4.6 1,557 28,927 5.4 1,032 27,631 3.7
- Others/Unknown 946 23,913 4.0 618 12,424 5.0 328 11,489 2.9
NYS Excluding NYC
- All Races 6,076 125,659 4.8 3,865 64,454 6.0 2,211 61,205 3.6
- Non-Hispanic White 4,250 88,538 4.8 2,724 45,323 6.0 1,526 43,215 3.5
- Non-Hispanic Black 705 12,042 5.9 420 6,087 6.9 285 5,955 4.8
- Hispanic 827 18,054 4.6 514 9,346 5.5 313 8,708 3.6
- Others/Unknown 294 7,025 4.2 207 3,698 5.6 87 3,327 2.6
New York City
- All Races 5,600 117,000 4.8 3,363 59,938 5.6 2,237 57,062 3.9
- Non-Hispanic White 1,449 32,878 4.4 899 16,861 5.3 550 16,017 3.4
- Non-Hispanic Black 1,737 28,730 6.0 1,010 14,770 6.8 727 13,960 5.2
- Hispanic 1,762 38,504 4.6 1,043 19,581 5.3 719 18,923 3.8
- Others/Unknown 652 16,888 3.9 411 8,726 4.7 241 8,162 3.0

Section 1 - Table 2
2005 Births - New York State Residents Number of Major Malformations Per Child

Number of Malformations Number of Children Percent
1 9,555 81.8
2 1,442 12.4
3 416 3.6
4 149 1.3
5 70 0.6
6 27 0.2
7 8 0.1
8 4 *
9 3 *
10 2 *
All Children 11,676 100.0
* - Less than 0.05%
Note: Total percent may not add to 100% due to rounding

Section 1 - Table 3
2005 Births - New York State Residents Percent of Live Births with One Major Malformation Sex by Race/Ethnicity and Residence

  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
New York State
- All Races 9,555 242,659 3.9 6,002 124,392 4.8 3,553 118,267 3.0
- Non-Hispanic White 4,649 121,416 3.8 3,018 62,184 4.9 1,631 59,232 2.8
- Non-Hispanic Black 2,000 40,772 4.9 1,186 20,857 5.7 814 19,915 4.1
- Hispanic 2,132 56,558 3.8 1,287 28,927 4.4 845 27,631 3.1
- Others/Unknown 774 23,913 3.2 511 12,424 4.1 263 11,489 2.3
NYS Excluding NYC
- All Races 4,943 125,659 3.9 3,213 64,454 5.0 1,730 61,205 2.8
- Non-Hispanic White 3,442 88,538 3.9 2,259 45,323 5.0 1,183 43,215 2.7
- Non-Hispanic Black 581 12,042 4.8 355 6,087 5.8 226 5,955 3.8
- Hispanic 679 18,054 3.8 434 9,346 4.6 245 8,708 2.8
- Others/Unknown 241 7,025 3.4 165 3,698 4.5 76 3,327 2.3
New York City
- All Races 4,612 117,000 3.9 2,789 59,938 4.7 1,823 57,062 3.2
- Non-Hispanic White 1,207 32,878 3.7 759 16,861 4.5 448 16,017 2.8
- Non-Hispanic Black 1,419 28,730 4.9 831 14,770 5.6 588 13,960 4.2
- Hispanic 1,453 38,504 3.8 853 19,581 4.4 600 18,923 3.2
- Others/Unknown 533 16,888 3.2 346 8,726 4.0 187 8,162 2.3

Section 1 - Table 4
2005 Births - New York State Residents Percent of Live Births with Two or More Major Malformations Sex by Race/Ethnicity and Residence

  Both Sexes Males Females
Race and Residence Infants Total Births % Infants Total Births % Infants Total Births %
New York State
- All Races 2,121 242,659 0.9 1,226 124,392 1.0 895 118,267 0.8
- Non-Hispanic White 1,050 121,416 0.9 605 62,184 1.0 445 59,232 0.8
- Non-Hispanic Black 442 40,772 1.1 244 20,857 1.2 198 19,915 1.0
- Hispanic 457 56,558 0.8 270 28,927 0.9 187 27,631 0.7
- Others/Unknown 172 23,913 0.7 107 12,424 0.9 65 11,489 0.6
NYS Excluding NYC
- All Races 1,133 125,659 0.9 652 64,454 1.0 481 61,205 0.8
- Non-Hispanic White 808 88,538 0.9 465 45,323 1.0 343 43,215 0.8
- Non-Hispanic Black 124 12,042 1.0 65 6,087 1.1 59 5,955 1.0
- Hispanic 148 18,054 0.8 80 9,346 0.9 68 8,708 0.8
- Others/Unknown 53 7,025 0.8 42 3,698 1.1 11 3,327 0.3
New York City
- All Races 988 117,000 0.8 574 59,938 1.0 414 57,062 0.7
- Non-Hispanic White 242 32,878 0.7 140 16,861 0.8 102 16,017 0.6
- Non-Hispanic Black 318 28,730 1.1 179 14,770 1.2 139 13,960 1.0
- Hispanic 309 38,504 0.8 190 19,581 1.0 119 18,923 0.6
- Others/Unknown 119 16,888 0.7 65 8,726 0.7 54 8,162 0.7