Congenital Malformations Registry - Summary Report

Section 1: Demographic Characteristics of Children Reported with Major Malformations

Introduction to Tables

These tables are based on children resident in New York State who were live born in 2006 and reported to the registry with major malformations. Since a new coding system began to be used in 1992, the list of major malformations has been revised (see Appendix 4). Thus, the prevalence in this report are not comparable to reports prior to 1992.

The overall occurrence of major malformations was 5.1% of live births. Male children have a higher rate of major malformations than female children (6.1% versus 4.0%, Table 1). This difference is consistent within different racial groups. The rates for major malformations are somewhat higher for black than for white children (6.4 % versus 4.9%). The major malformation rate among children with residence at birth in New York State excluding New York City was comparable to that among children with residence at birth in New York City (5.0% versus 5.2%). The smaller number of births in the "other" racial category makes these rates difficult to interpret.

About 78% of children reported with major malformations have only one major malformation (Table 2). Since most children had one major malformation, the race-sex patterns seen for all major malformations are similar to the patterns seen in children with a single major malformation (Table 3). All race-sex groups for children with multiple major malformations showed little variation (Table 4).

Section 1, Table 1
2006 Births-New York State Residents
Percent of Live Births with One or More Major Malformations
Sex by Race/Ethnicity and Residence

Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
- All Races 12,277 242,365 5.1 7,516 124,224 6.1 4,761 118,141 4.0
- Non-Hispanic White 5,922 119,734 4.9 3,737 61,406 6.1 2,185 58,328 3.7
- Non-Hispanic Black 2,566 40,367 6.4 1,487 20,533 7.2 1,079 19,834 5.4
- Hispanic 2,734 57,555 4.8 1,644 29,420 5.6 1,090 28,135 3.9
- Others/Unknown 1,055 24,709 4.3 648 12,865 5.0 407 11,844 3.4
- All Races 6,343 127,461 5.0 3,942 65,384 6.0 2,401 62,077 3.9
- Non-Hispanic White 4,391 88,253 5.0 2,782 45,241 6.1 1,609 43,012 3.7
- Non-Hispanic Black 778 12,539 6.2 438 6,402 6.8 340 6,137 5.5
- Hispanic 836 19,211 4.4 502 9,826 5.1 334 9,385 3.6
- Others/Unknown 338 7,458 4.5 220 3,915 5.6 118 3,543 3.3
- All Races 5,934 114,904 5.2 3,574 58,840 6.1 2,360 56,064 4.2
- Non-Hispanic White 1,531 31,481 4.9 955 16,165 5.9 576 15,316 3.8
- Non-Hispanic Black 1,788 27,828 6.4 1,049 14,131 7.4 739 13,697 5.4
- Hispanic 1,898 38,344 4.9 1,142 19,594 5.8 756 18,750 4.0
- Others/Unknown 717 17,251 4.2 428 8,950 4.8 289 8,301 3.5

Section 1, Table 2
2006 Births-New York State Residents
Number of Major Malformations Per Child

Number of Malformations Number of Children Percent
1 9,626 78.4
2 1,644 13.4
3 554 4.5
4 250 2.0
5 95 0.8
6 51 0.4
7 27 0.2
8 18 0.1
9 8 0.1
10 4 <0.05
All Children 12,277 100.0
Note: Total percent may not add to 100, due to rounding

Section 1, Table 3
2006 Births-New York State Residents
Percent of Live Births with One Major Malformation
Sex by Race/Ethnicity and Residence

Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
- All Races 9,626 242,365 4.0 6,025 124,224 4.9 3,601 118,141 3.0
- Non-Hispanic White 4,632 119,734 3.9 2,993 61,406 4.9 1,639 58,328 2.8
- Non-Hispanic Black 2,036 40,367 5.0 1,183 20,533 5.8 853 19,834 4.3
- Hispanic 2,157 57,555 3.7 1,346 29,420 4.6 811 28,135 2.9
- Others/Unknown 801 24,709 3.2 503 12,865 3.9 298 11,844 2.5
- All Races 4,943 127,461 3.9 3,164 65,384 4.8 1,779 62,077 2.9
- Non-Hispanic White 3,406 88,253 3.9 2,217 45,241 4.9 1,189 43,012 2.8
- Non-Hispanic Black 619 12,539 4.9 353 6,402 5.5 266 6,137 4.3
- Hispanic 658 19,211 3.4 417 9,826 4.2 241 9,385 2.6
- Others/Unknown 260 7,458 3.5 177 3,915 4.5 83 3,543 2.3
- All Races 4,683 114,904 4.1 2,861 58,840 4.9 1,822 56,064 3.2
- Non-Hispanic White 1,226 31,481 3.9 776 16,165 4.8 450 15,316 2.9
- Non-Hispanic Black 1,417 27,828 5.1 830 14,131 5.9 587 13,697 4.3
- Hispanic 1,499 38,344 3.9 929 19,594 4.7 570 18,750 3.0
- Others/Unknown 541 17,251 3.1 326 8,950 3.6 215 8,301 2.6

Section 1, Table 4
2006 Births-New York State Residents
Percent of Live Births with Two or More Major Malformation
Sex by Race/Ethnicity and Residence

Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
- All Races 2,651 242,365 1.1 1,491 124,224 1.2 1,160 118,141 1.0
- Non-Hispanic White 1,290 119,734 1.1 744 61,406 1.2 546 58,328 0.9
- Non-Hispanic Black 530 40,367 1.3 304 20,533 1.5 226 19,834 1.1
- Hispanic 577 57,555 1.0 298 29,420 1.0 279 28,135 1.0
- Others/Unknown 254 24,709 1.0 145 12,865 1.1 109 11,844 0.9
- All Races 1,400 127,461 1.1 778 65,384 1.2 622 62,077 1.0
- Non-Hispanic White 985 88,253 1.1 565 45,241 1.2 420 43,012 1.0
- Non-Hispanic Black 159 12,539 1.3 85 6,402 1.3 74 6,137 1.2
- Hispanic 178 19,211 0.9 85 9,826 0.9 93 9,385 1.0
- Others/Unknown 78 7,458 1.0 43 3,915 1.1 35 3,543 1.0
- All Races 1,251 114,904 1.1 713 58,840 1.2 538 56,064 1.0
- Non-Hispanic White 305 31,481 1.0 179 16,165 1.1 126 15,316 0.8
- Non-Hispanic Black 371 27,828 1.3 219 14,131 1.5 152 13,697 1.1
- Hispanic 399 38,344 1.0 213 19,594 1.1 186 18,750 1.0
- Others/Unknown 176 17,251 1.0 102 8,950 1.1 74 8,301 0.9