Congenital Malformations Registry - Summary Report, 2007

Section 1: Demographic Characteristics of Children Reported with Major Malformations

Introduction to Tables

These tables are based on children resident in New York State who were live born in 2007 and reported to the registry with major malformations. Since a new coding system began to be used in 1992, the list of major malformations has been revised (see Appendix 4). Thus, the prevalence in this report are not comparable to reports prior to 1992.

The overall occurrence of major malformations was 5.0% of live births. Male children have a higher rate of major malformations than female children (6.0% versus 3.9%, Table 1). This difference is consistent within different racial groups. The rates for major malformations are somewhat higher for black than for white children (6.0 % versus 5.0%). The major malformation rate among children with residence at birth in New York State excluding New York City was comparable to that among children with residence at birth in New York City (5.1% versus 4.8%). The smaller number of births in the "other" racial category makes these rates difficult to interpret.

About 78.4% of children reported with major malformations have only one major malformation (Table 2). Since most children had one major malformation, the race-sex patterns seen for all major malformations are similar to the patterns seen in children with a single major malformation (Table 3). All race-sex groups for children with multiple major malformations showed little variation (Table 4).

Section 1, Table 1

2007 Births-New York State Residents
Percent of Live Births with One or More Major Malformations
Sex by Race/Ethnicity and Residence
Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
New York State
All Races 12,220 245,338 5.0 7,505 125,245 6.0 4,715 120,093 3.9
- Non-Hispanic White 6,010 119,779 5.0 3,790 61,438 6.2 2,220 58,341 3.8
- Non-Hispanic Black 2,455 40,680 6.0 1,432 20,641 6.9 1,023 20,039 5.1
- Hispanic 2,715 58,244 4.7 1,637 29,495 5.6 1,078 28,749 3.7
- Others/Unknown 1,040 26,635 3.9 646 13,671 4.7 394 12,964 3.0
New York State, Excluding New York City
All Races 6,498 127,308 5.1 4,088 65,078 6.3 2,410 62,230 3.9
- Non-Hispanic White 4,430 87,266 5.1 2,832 44,845 6.3 1,598 42,421 3.8
- Non-Hispanic Black 786 12,671 6.2 464 6,392 7.3 322 6,279 5.1
- Hispanic 919 19,713 4.7 572 9,967 5.7 347 9,746 3.6
- Others/Unknown 363 7,658 4.7 220 3,874 5.7 143 3,784 3.8
New York City
All Races 5,722 118,030 4.8 3,417 60,167 5.7 2,305 57,863 4.0
- Non-Hispanic White 1,580 32,513 4.9 958 16,593 5.8 622 15,920 3.9
- Non-Hispanic Black 1,669 28,009 6.0 968 14,249 6.8 701 13,760 5.1
- Hispanic 1,796 38,531 4.7 1,065 19,528 5.5 731 19,003 3.8
- Others/Unknown 677 18,977 3.6 426 9,797 4.3 251 9,180 2.7

Section 1, Table 2

2007 Births-New York State Residents
Number of Major Malformations Per Child
Number of Malformations Number of Children Percent
1 9,584 78.4
2 1,607 13.2
3 553 4.5
4 233 1.9
5 118 1.0
6 61 0.5
7 29 0.2
8 17 0.1
9 10 0.1
10 5 *
11 2 *
12 1 *
All Children 12,220 100.0
* - Less than 0.05%
Note: Total percent may not add to 100% due to rounding

Section 1, Table 3

2007 Births-New York State Residents
Percent of Live Births with One Major Malformation
Sex by Race/Ethnicity and Residence
Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
New York State
All Races 9,584 245,338 3.9 5,955 125,245 4.8 3,629 120,093 3.0
- Non-Hispanic White 4,758 119,779 4.0 3,053 61,438 5.0 1,705 58,341 2.9
- Non-Hispanic Black 1,920 40,680 4.7 1,130 20,641 5.5 790 20,039 3.9
- Hispanic 2,106 58,244 3.6 1,266 29,495 4.3 840 28,749 2.9
- Others/Unknown 800 26,635 3.0 506 13,671 3.7 294 12,964 2.3
New York State, Excluding New York City
All Races 5,100 127,308 4.0 3,242 65,078 5.0 1,858 62,230 3.0
- Non-Hispanic White 3,508 87,266 4.0 2,279 44,845 5.1 1,229 42,421 2.9
- Non-Hispanic Black 602 12,671 4.8 348 6,392 5.4 254 6,279 4.0
- Hispanic 710 19,713 3.6 447 9,967 4.5 263 9,746 2.7
- Others/Unknown 280 7,658 3.7 168 3,874 4.3 112 3,784 3.0
New York City
All Races 4,484 118,030 3.8 2,713 60,167 4.5 1,771 57,863 3.1
- Non-Hispanic White 1,250 32,513 3.8 774 16,593 4.7 476 15,920 3.0
- Non-Hispanic Black 1,318 28,009 4.7 782 14,249 5.5 536 13,760 3.9
- Hispanic 1,396 38,531 3.6 819 19,528 4.2 577 19,003 3.0
- Others/Unknown 520 18,977 2.7 338 9,797 3.5 182 9,180 2.0

Section 1, Table 4

2007 Births-New York State Residents
Percent of Live Births with Two or More Major Malformations
Sex by Race/Ethnicity and Residence
Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
New York State
All Races 2,636 245,338 1.1 1,550 125,245 1.2 1,086 120,093 0.9
- Non-Hispanic White 1,252 119,779 1.0 737 61,438 1.2 515 58,341 0.9
- Non-Hispanic Black 535 40,680 1.3 302 20,641 1.5 233 20,039 1.2
- Hispanic 609 58,244 1.0 371 29,495 1.3 238 28,749 0.8
- Others/Unknown 240 26,635 0.9 140 13,671 1.0 100 12,964 0.8
New York State, Excluding New York City
All Races 1,398 127,308 1.1 846 65,078 1.3 552 62,230 0.9
- Non-Hispanic White 922 87,266 1.1 553 44,845 1.2 369 42,421 0.9
- Non-Hispanic Black 184 12,671 1.5 116 6,392 1.8 68 6,279 1.1
- Hispanic 209 19,713 1.1 125 9,967 1.3 84 9,746 0.9
- Others/Unknown 83 7,658 1.1 52 3,874 1.3 31 3,784 0.8
New York City
All Races 1,238 118,030 1.0 704 60,167 1.2 534 57,863 0.9
- Non-Hispanic White 330 32,513 1.0 184 16,593 1.1 146 15,920 0.9
- Non-Hispanic Black 351 28,009 1.3 186 14,249 1.3 165 13,760 1.2
- Hispanic 400 38,531 1.0 246 19,528 1.3 154 19,003 0.8
- Others/Unknown 157 18,977 0.8 88 9,797 0.9 69 9,180 0.8