Congenital Malformations Registry - Summary Report, 2008

Section I: Demographic Characteristics of Children Reported with Major Malformations

Introduction to Tables

These tables are based on children resident in New York State who were live born in 2008 and reported to the registry with major malformations. Since a new coding system began to be used in 1992, the list of major malformations has been revised (see LINK Appendix 4). Thus, the prevalence in this report are not comparable to reports prior to 1992.

The overall occurrence of major malformations was 5.1% of live births. Male children have a higher rate of major malformations than female children (6.0% versus 4.0%, Table 1). This difference is consistent within different racial groups. The rates for major malformations are somewhat higher for black than for white children (6.6 % versus 5.0%). The major malformation rate among children with residence at birth in New York State excluding New York City was comparable to that among children with residence at birth in New York City (5.2% versus 4.9%). The smaller number of births in the "other" racial category makes these rates difficult to interpret.

About 79.0% of children reported with major malformations have only one major malformation (Table 2). Since most children had one major malformation, the race-sex patterns seen for all major malformations are similar to the patterns seen in children with a single major malformation (Table 3). All race-sex groups for children with multiple major malformations showed little variation (Table 4).

Section 1, Table 1

2007 Births-New York State Residents
Percent of Live Births with One or More Major Malformations
Sex by Race/Ethnicity and Residence
Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
New York State
All Races 12,462 246,655 5.1 7,643 126,673 6.0 4,819 119,982 4.0
Non-Hispanic white 5,947 119,196 5.0 3,751 61,335 6.1 2,196 57,861 3.8
Non-Hispanic black 2,636 40,216 6.6 1,519 20,476 7.4 1,117 19,740 5.7
Hispanic 2,680 59,003 4.5 1,655 30,364 5.5 1,025 28,639 3.6
Others/Unknown 1,199 28,240 4.2 718 14,498 5.0 481 13,742 3.5
NYS Excluding NYC
All Races 6,521 125,071 5.2 4,060 64,165 6.3 2,461 60,906 4.0
Non-Hispanic white 4,351 84,705 5.1 2,759 43,570 6.3 1,592 41,135 3.9
Non-Hispanic black 892 12,628 7.1 516 6,485 8.0 376 6,143 6.1
Hispanic 917 19,905 4.6 575 10,215 5.6 342 9,690 3.5
Others/Unknown 361 7,833 4.6 210 3,895 5.4 151 3,938 3.8
New York City
All Races 5,941 121,584 4.9 3,583 62,508 5.7 2,358 59,076 4.0
Non-Hispanic white 1,596 34,491 4.6 992 17,765 5.6 604 16,726 3.6
Non-Hispanic black 1,744 27,588 6.3 1,003 13,991 7.2 741 13,597 5.4
Hispanic 1,763 39,098 4.5 1,080 20,149 5.4 683 18,949 3.6
Others/Unknown 838 20,407 4.1 508 10,603 4.8 330 9,804 3.4

Section 1, Table 2

2007 Births-New York State Residents
Number of Major Malformations Per Child
Number of Malformations Number of Children Percent
1 9,848 79.0
2 1,637 13.1
3 520 4.2
4 221 1.8
5 108 0.9
6 51 0.4
7 40 0.3
8 16 0.1
9 11 0.1
10 6 *
11 2 *
12 2 *
All Children 12,462 100.0
* - Less than 0.05%
Note: Total percent may not add to 100% due to rounding

Section 1, Table 3

2007 Births-New York State Residents
Percent of Live Births with One Major Malformation
Sex by Race/Ethnicity and Residence
Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
New York State
All Races 9,848 246,655 4.0 6,155 126,673 4.9 3,693 119,982 3.1
Non-Hispanic white 4,682 119,196 3.9 3,026 61,335 4.9 1,656 57,861 2.9
Non-Hispanic black 2,118 40,216 5.3 1,239 20,476 6.1 879 19,740 4.5
Hispanic 2,090 59,003 3.5 1,310 30,364 4.3 780 28,639 2.7
Others/Unknown 958 28,240 3.4 580 14,498 4.0 378 13,742 2.8
NYS Excluding NYC
All Races 5,127 125,071 4.1 3,262 64,165 5.1 1,865 60,906 3.1
Non-Hispanic white 3,410 84,705 4.0 2,226 43,570 5.1 1,184 41,135 2.9
Non-Hispanic black 723 12,628 5.7 422 6,485 6.5 301 6,143 4.9
Hispanic 721 19,905 3.6 452 10,215 4.4 269 9,690 2.8
Others/Unknown 273 7,833 3.5 162 3,895 4.2 111 3,938 2.8
New York City
All Races 4,721 121,584 3.9 2,893 62,508 4.6 1,828 59,076 3.1
Non-Hispanic white 1,272 34,491 3.7 800 17,765 4.5 472 16,726 2.8
Non-Hispanic black 1,395 27,588 5.1 817 13,991 5.8 578 13,597 4.3
Hispanic 1,369 39,098 3.5 858 20,149 4.3 511 18,949 2.7
Others/Unknown 685 20,407 3.4 418 10,603 3.9 267 9,804 2.7

Section 1, Table 4

2007 Births-New York State Residents
Percent of Live Births with Two or More Major Malformations
Sex by Race/Ethnicity and Residence
Race and Residence Both Sexes Males Females
Infants Total Births Percent Infants Total Births Percent Infants Total Births Percent
New York State
All Races 2,614 246,655 1.1 1,488 126,673 1.2 1,126 119,982 0.9
Non-Hispanic white 1,265 119,196 1.1 725 61,335 1.2 540 57,861 0.9
Non-Hispanic black 518 40,216 1.3 280 20,476 1.4 238 19,740 1.2
Hispanic 590 59,003 1.0 345 30,364 1.1 245 28,639 0.9
Others/Unknown 241 28,240 0.9 138 14,498 1.0 103 13,742 0.7
NYS Excluding NYC
All Races 1,394 125,071 1.1 798 64,165 1.2 596 60,906 1.0
Non-Hispanic white 941 84,705 1.1 533 43,570 1.2 408 41,135 1.0
Non-Hispanic black 169 12,628 1.3 94 6,485 1.4 75 6,143 1.2
Hispanic 196 19,905 1.0 123 10,215 1.2 73 9,690 0.8
Others/Unknown 88 7,833 1.1 48 3,895 1.2 40 3,938 1.0
New York City
All Races 1,220 121,584 1.0 690 62,508 1.1 530 59,076 0.9
Non-Hispanic white 324 34,491 0.9 192 17,765 1.1 132 16,726 0.8
Non-Hispanic black 349 27,588 1.3 186 13,991 1.3 163 13,597 1.2
Hispanic 394 39,098 1.0 222 20,149 1.1 172 18,949 0.9
Others/Unknown 153 20,407 0.7 90 10,603 0.8 63 9,804 0.6