Table 46a: Leading Causes of Premature Death (Prior to Age 65) and Years of Life Lost, New York State - 2021

Cause of Death Total Male Female
Deaths YLL Deaths YLL Deaths YLL
Total 44,180 655,444 28,159 428,334 16,020 227,074
Acquired Immune Deficiency Syndrome (AIDS) 290 4,002 209 2,797 81 1,205
Malignant Neoplasms 8,256 80,477 4,162 39,189 4,094 41,288
   Buccal Cavity and Pharynx 160 1,443 128 1,156 32 287
   Digestive Organs and Peritoneum 2,541 23,376 1,563 14,046 978 9,330
   Respiratory System 1,700 12,092 973 6,928 727 5,164
     Trachea, Bronchus and Lung 1,606 11,219 904 6,257 702 4,962
   Breast 776 8,678 7 61 769 8,617
   Genital Organs 820 7,502 156 1,102 664 6,400
   Urinary Organs 282 2,312 200 1,575 82 737
   Other and Unspecified Sites 1,410 17,776 801 10,065 609 7,711
   Lymphatic and Hematopoietic Tissues 567 7,298 334 4,256 233 3,042
Diabetes Mellitus 1,231 13,231 803 8,842 428 4,389
Diseases of the Circulatory System 8,968 91,029 6,147 62,128 2,821 28,901
   Diseases of the Heart 7,197 71,987 5,077 50,735 2,120 21,252
     Hypertension with Heart Disease 1,040 11,168 702 7,528 338 3,640
     Acute Myocardial Infarction 1,003 9,012 763 7,087 240 1,925
     Other Ischemic Heart Diseases+ 3,554 30,384 2,608 22,775 946 7,609
     Other Diseases of the Heart 1,600 21,423 1,004 13,345 596 8,078
   Hypertension with or without Renal Disease 388 3,410 231 2,010 157 1,400
   Cerebrovascular Disease 971 10,249 577 5,970 394 4,279
   Other Diseases of the Circulatory System 412 5,383 262 3,413 150 1,970
Pneumonia 560 6,005 334 3,351 226 2,654
Chronic Lower Respiratory Disease (CLRD) 816 6,793 432 3,620 384 3,173
Cirrhosis of Liver 1,186 15,533 781 10,066 405 5,467
Congenital Anomalies 386 16,322 209 8,677 177 7,645
Certain Conditions Originating in the Perinatal Period 427 27,681 233 15,090 194 12,591
Accidents (Total) 7,134 158,064 5,297 117,365 1,837 40,699
   Motor Vehicle 1,023 27,732 803 21,613 220 6,119
   Drownings 108 3,528 80 2,560 28 968
   Falls 321 4,296 246 3,429 75 867
   Poisonings 5,161 109,544 3,768 79,808 1,393 29,736
Suicide 1,318 31,947 1,009 24,145 308 7,766
Homicide and Legal Intervention 877 28,546 748 24,381 129 4,165
COVID-19 4,901 51,804 3,070 32,574 1,831 19,230
All Other Causes 7,830 124,010 4,725 76,109 3,105 47,901

Total - Total Deaths include deaths with sex "Not Stated".

YLL - Years of Life Lost is calculated by subtracting age at death from 65.