Table 46c: Leading Causes of Premature Death (Prior to Age 65) and Years of Life Lost, New York City - 2021

Cause of Death Total Male Female
Deaths YLL Deaths YLL Deaths YLL
Total 17,473 261,077 11,218 172,289 6,254 88,752
Acquired Immune Deficiency Syndrome (AIDS) 225 3,065 156 2,079 69 986
Malignant Neoplasms 3,094 32,462 1,516 15,772 1,578 16,690
   Buccal Cavity and Pharynx 71 719 57 548 14 171
   Digestive Organs and Peritoneum 1,026 10,006 634 6,049 392 3,957
   Respiratory System 514 3,957 306 2,373 208 1,584
     Trachea, Bronchus and Lung 473 3,541 277 2,036 196 1,505
   Breast 339 3,928 2 22 337 3,906
   Genital Organs 361 3,375 73 534 288 2,841
   Urinary Organs 78 619 49 385 29 234
   Other and Unspecified Sites 478 6,779 260 3,977 218 2,802
   Lymphatic and Hematopoietic Tissues 227 3,079 135 1,884 92 1,195
Diabetes Mellitus 467 5,285 306 3,663 161 1,622
Diseases of the Circulatory System 3,815 38,718 2,587 26,520 1,228 12,198
   Diseases of the Heart 3,065 30,496 2,132 21,609 933 8,887
     Hypertension with Heart Disease 599 6,552 399 4,517 200 2,035
     Acute Myocardial Infarction 291 2,787 222 2,286 69 501
     Other Ischemic Heart Diseases+ 1,693 14,212 1,223 10,598 470 3,614
     Other Diseases of the Heart 482 6,945 288 4,208 194 2,737
   Hypertension with or without Renal Disease 190 1,708 109 953 81 755
   Cerebrovascular Disease 397 4,288 235 2,432 162 1,856
   Other Diseases of the Circulatory System 163 2,226 111 1,526 52 700
Pneumonia 252 2,554 153 1,401 99 1,153
Chronic Lower Respiratory Disease (CLRD) 246 2,642 124 1,317 122 1,325
Cirrhosis of Liver 367 5,274 262 3,753 105 1,521
Congenital Anomalies 129 6,285 75 3,491 54 2,794
Certain Conditions Originating in the Perinatal Period 172 11,148 90 5,818 82 5,330
Accidents (Total) 2,865 56,279 2,145 42,139 720 14,140
   Motor Vehicle 278 8,089 225 6,429 53 1,660
   Drownings 34 1,168 27 944 7 224
   Falls 139 1,988 110 1,573 29 415
   Poisonings 2,223 40,686 1,635 29,862 588 10,824
Suicide 421 10,661 312 7,810 108 2,815
Homicide and Legal Intervention 464 15,433 409 13,750 55 1,683
COVID-19 2,016 21,210 1,269 13,387 747 7,823
All Other Causes 2,940 50,061 1,814 31,389 1,126 18,672

Total - Total Deaths include deaths with sex "Not Stated".

YLL - Years of Life Lost is calculated by subtracting age at death from 65.