Mpox Vaccination

New Yorkers who may have been exposed to mpox in areas with high levels of transmission may be eligible for the JYNNEOS vaccine.

What is the JYNNEOS vaccine?

JYNNEOS is a vaccine licensed by the U.S. Food and Drug Administration (FDA) as a two-dose series for the prevention of mpox among adults ages 18 years and older. If given before exposure or within 4 days of exposure, this vaccine may reduce the likelihood of infection, and within 14 days, it may reduce severity of symptoms.

The two vaccine doses are given 28 days apart, and New Yorkers are considered fully vaccinated two weeks after their second dose. People who get vaccinated should continue to take steps to protect themselves from infection by avoiding close, skin-to-skin contact, including intimate contact, with someone who has mpox.

Availability of the JYNNEOS vaccine:

Statewide eligibility currently includes the following New Yorkers:

  • Individuals with recent exposure to a suspected or confirmed mpox case within the past 14 days.
  • Those at high risk of a recent exposure to mpox, including gay men and members of the bisexual, transgender, and gender non-conforming community and other communities of men who have sex with men and who have engaged in intimate or skin-to-skin contact with others in the past 14 days areas where mpox is spreading.
  • Individuals who have had skin-to-skin contact with someone in a social network experiencing mpox activity, including men who have sex with men who meet partners through an online website, digital application ("app"), or social event, such as a bar or party.
  • Any individual that may be at risk of future exposure to infection with mpox, even though they are not at high risk of a recent exposure to mpox.

Where can I get the JYNNEOS vaccine?

People identified by a local health department as exposed to a suspected or confirmed mpox case in the past 14 days should work directly with their health department and healthcare provider to discuss obtaining the JYNNEOS vaccine.

Local county health departments will administer the vaccine directly and are establishing their own appointment processes. Please refer to county webpages for more information.

Where can I learn more about the JYNNEOS vaccine?

New Yorkers can learn more about the JYNNEOS vaccine, including the risks and benefits, here. To better understand the protective benefits of the JYNNEOS vaccine in the current outbreak U.S., public health agencies are collecting data to study any side effects, the extent of protection, and whether the way a person was infected makes any difference in how well the vaccine protects them.